Cynomix is an advanced technology developed for four years under DARPA's Cyber Genome program. It was evaluated by DARPA and MIT Lincoln Labs, and rated as the highest among all DARPA teams in its category. The goal of DARPA's Cyber Genome program was to map the genome for malware, under the premise that while over 300,000 malware strains are released daily, most are variants of a manageable number of malware families. Cynomix was conceived as a technology for identifying the unique genetic markers held in common for each malware family, and for clustering them using machine learning algorithms applied to big data sets. These algorithms cluster thousands of labeled malware ingested daily, which enables Cynomix to stay current with the newest emerging threats. This approach gives Cynomix unmatched powers of detection by analyzing a broad sampling of malware in the wild, without having to see every minor malware variation.